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Swansea Uni to deliver advanced therapies

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A significant opportunity: University a centre for cell and gene therapies

SWANSEA U​NIVERSITY’S​ Medical School, through its partnership with Abertawe Bro Morgannwg University Health Board, is to be one of the centres to deliver advanced medical therapies to Wales, which is part of a major investment announced by Welsh Blood Services.

A recently formed health consortium, jointly led by the Welsh Blood Service (on behalf of NHS Wales) and the National Institute for Health Research Birmingham Biomedical Research Centre, has been awarded £7.3M of UK Government funding to ensure more patients benefit from a new generation of breakthrough therapies.

£1.5M will come directly to NHS Wales and £550K to Trakcel, a Welsh software company developing scheduling/tracking software for advanced therapies which is based upon technology developed at Swansea University.

The funding will support the Welsh Government’s commitment to developing an Advanced Therapies Strategy which will enable these therapies to be brought to Welsh patients and Advanced Therapy Medicinal Product (ATMP) companies to reach the clinical market, whilst building expertise, capability and capacity across NHS Wales to benefit patient outcomes.

Speaking of the award, Frank Atherton, Chief Medical Officer for Wales, said: “We welcome the announcement of the successful partnership between Birmingham, Nottingham and Wales NHS centres in bidding for Innovate UK monies. The project is aligned with our ambition to support the development, availability and adoption of new innovative therapies for patients in Wales. Cell and gene-based advanced therapies offer exciting opportunities, not only for the way we treat people with previously incurable conditions, but also how we work together with industry and NHS Wales in bringing these treatments from bench to bedside.”

The NHS Wales role in the MW-ATTC consortium was led by the Welsh Blood Service, with support from Abertawe Bro Morgannwg and Cardiff & Vale University Health Boards along with the Life Sciences Hub Wales Special Interest Group on Cell and Gene Therapy, which brings together expertise from the Welsh NHS, Universities and industry in the Life Science sector.

As part of the contract award, one of the first advanced therapy treatment sites in Wales will be established within Abertawe Bro Morgannwg at the Joint Clinical Research Facility (JCRF) at Swansea University’s Medical School. The focus of the centre will be to develop the infrastructure, processes and skilled workforce required to enable patients to be cared for, from diagnosis through to post-treatment follow up.

Cath O’Brien, Director of the Welsh Blood Service and MW-ATTC Co-Director, said: “A significant opportunity exists to position Wales as a leader in clinical trial and routine delivery of cell and gene therapies to maximise Welsh patient benefit and opportunities for the national economy. The Welsh Government is committed to exploring these revolutionary developments in healthcare and we are excited to have worked alongside our consortium partners to secure funding through what was a highly competitive tendering process.”

One of the first products that will pass through the Welsh centres is that being developed by one of the consortium partners, Rexgenero and is intended to prevent the need for diabetes-related lower limb amputations for some no option patients. The incidence of diabetes is continuing to increase in Wales and already accounts for ~10% of the NHS Wales budget (£500M) with 200, 000 sufferers today rising to an estimated 500,000 by 2025. Currently around 2000 patients in Wales have non-healing lower limb ulcers that result in approximately 330 amputations per year.

The Midlands & Wales Advanced Therapy Treatment Centre (MW-ATTC) will identify barriers, challenges and solutions to facilitate future deployment and adoption of these transformative therapies within the UK healthcare system.

Advanced treatments, such as cell and gene therapies, show great promise for patients with chronic and terminal conditions that currently cannot be cured. Unlike conventional medicines, these new approaches often aim to selectively remove, repair, replace, regenerate and re-engineer a patient’s own genes, cells and tissues to restore normal function. The project will include potential treatments for arthritis, liver disease, several types of cancer, and diabetic ulcers.

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Education

Tir Coed build outdoor classroom for Cross Hands Primary

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The local charity Tir Coed teamed up with Cross Hands Primary School to design and install a locally grown woodland shelter to enable primary school pupils to benefit from outdoor lessons-even when
the rain pours!

Last year Cross Hands Primary School received funding from Carmarthenshire is Kind for their intergenerational project. The project brought the schoolchildren together with older people in the community. Through intergenerational activities, everyone involved increases social connectedness, reduces social isolation, learns from one another and has a great time!

Before the lockdown, Tir Coed was contracted to lead a group mainly made up of parents from the school on a shelter-building course. The attendees would gain knowledge and skills and the children and the older people would be able to use the shelter, a third generation now included in this
fantastic project. The plans, however, had to change due to restrictions and in an effort to have it ready for the children when they returned to school, three intrepid Activity Leaders braved the wet August weather to build the beautiful shelter .

Studies have shown that being in the outdoors significantly reduces the risk of spreading the Corona Virus. With this addition to their already impressive outdoor area, it is hoped that more learning can
take place outside the classroom. Deputy Head, Emma Walters said, “It looks amazing! I am very impressed with the shelter and I cannot thank Tir Coed enough for organising this. Additional covered space in the outdoors will mean that we can take more learning into our lovely nature
area.”

If you would like to find out more about the work of Tir Coed or have a project you would like our help with you can contact Nancy, the Carmarthenshire Coordinator: carms@tircoed.org.uk

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Vital support for job seekers and employers in West Wales

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TO MATCH job seekers with employers and career agencies across West Wales, a virtual jobs fair is taking place on Wednesday 9 September.

The free online event will be hosted by Working Wales, which is delivered by Careers Wales, and is in partnership with Job Centre Plus teams across West Wales and the south west and mid Wales Regional Learning and Skills Partnership.

Now, more than ever, job seekers and employers are relying on online support to find jobs and fill vacancies.

The event will run through Working Wales’ Facebook channels and will be split into two regional events covering West Wales mid and south. 10am-11amis for job seekers and employers in Bridgend, Rhondda Cynon Taff, Powys and Neath Port Talbot. 2pm-3pm will focus on Carmarthenshire, Pembrokeshire, Ceredigion and Swansea.

Attendees for the free event will have access to a wide variety of job vacancies from many sectors across West Wales as well as expert careers advice to support with job applications.

Working Wales isfunded by the Welsh Government and the European Social Fund and was launched by the Minister for Economy, Transport and North Wales, Ken Skatesin May 2019.

Within the first year the service has directly assisted over 37,000 people across Wales. Careers Wales chief executive, Nikki Lawrence said “We are delighted to be working with our partners in the west to deliver a virtual jobs fair. Our careers advice and guidance is a vital part of supporting the economy during this pandemic, and these online events allow us to effectively and safely continue reaching and supporting our customers during these challenging times.”

To register your interest in these events, follow Working Wales on Facebook @WorkingWales. If you are an employer with vacancies to fill please also get in touch.

Available to anyone over the age of 16,Working Wales provides a one-to-one, tailored employability advice and guidance service, supporting people across Wales with job searching, CV writing, interview preparation, training and upskilling as well as with redundancy support.

For more information on Working Wales visit: www.workingwales.gov.wales or call 0800 028 4844

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Virtual graduation for Class of 2020

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UWTSD is looking forward to hosting a series of online events to celebrate the academic success of the ‘Class of 2020’.
With formal degree ceremonies due to be held at a later date, UWTSD organised a series of digital celebrations that will take place on Tuesday, July 21, Wednesday, July 22, and Thursday, July 2.
Providing students with an opportinuty to celebrate their academic and personal achievements, the digital events included video messages from the Vice Chancellor, the Provosts, Universty Fellows as well as staff and fellow students.
“The Class of 2020 digital celebrations allowed us to come together – as family, friends and members of the University community – to mark our students’ academic achievements,” says Professor Medwin Hughes DL, UWTSD Vice Chancellor.
“These have been very difficult times for us all and yet students have succeeded, and these digital events help us to celebrate that academic achievement. Indeed, I would like to thank our students for the way in which they’ve responded to this pandemic and the way in which they’ve worked with the University. These celebrations were an opportunity for us to wish our students well for the future and to celebrate their hard work and success.”
Gwilym Dyfri Jones, Provost of the University’s Carmarthen and Lampeter campuses, said: “These virtual celebrations were an opportunity for the University to congratulate its Class of 2020 and to show that it is thinking of each and every one of the graduates at these unprecedented time,.
“It is also an opportunity for us to share our gratitude with the students for their valued contributions to the life of the university and its various campuses during these last few years,” he adds.
“We are proud of our graduates’ achievements and relished celebrating their successes with them in a virtual environment next week.”
Professor Ian Walsh, Provost of UWTSD’s Swansea and Cardiff campuses is immensely proud of the graduates’ achievements.
“During this difficult final term, the students of UWTSD have demonstrated the true meaning of the phrase ‘the best of us’,” says Professor Walsh. “It is fitting that the University takes a moment to celebrate the striking success of the class of 2020.
“Their hard won achievements demonstrate that this generation of UWTSD graduates possess all the necessary resourcefulness, resilience and determination to overcome the most challenging circumstances. In the process they have made their families, friends and lecturers extremely proud.”
James Mills, Group President of the Students’ Union at UWTSD also acknowledges the unprecedented challenges faced by the Class of 2020 and echoes the pride felt by all at UWTSD: “On behalf of everyone here at your Students’ Union we are incredibly proud of the hard work and success of our students over the past few months under incredibly difficult and challenging circumstances and adapted well to online learning.
“We also look forward to welcoming our students back in the next year for their graduation ceremonies on their respective campuses,” he adds.
Due to the Covid-19 pandemic, UWTSD – like all other Universities – had to respond swiftly to the lockdown restrictions with teaching moving on-line and celebrations such as graduation, being postponed.
However, UWTSD has already announced that its campuses will be open and ready to start teaching at the beginning of the new academic year, subject to government guidelines. The University is planning a blended delivery pattern for its programmes in Wales which means a combination of online delivery and on-campus teaching, when it is appropriate to do so.
The University is working to a detailed plan which anticipates various scenarios around the coronavirus context and government directives, much in keeping with the Welsh Government’s traffic light system.
It aims to ensure the safe return of students and staff to the campuses whilst also enabling as much face-to-face teaching as possible in order to ensure that students can enjoy an academic and social programme.

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