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Swansea Uni to deliver advanced therapies

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A significant opportunity: University a centre for cell and gene therapies

SWANSEA U​NIVERSITY’S​ Medical School, through its partnership with Abertawe Bro Morgannwg University Health Board, is to be one of the centres to deliver advanced medical therapies to Wales, which is part of a major investment announced by Welsh Blood Services.

A recently formed health consortium, jointly led by the Welsh Blood Service (on behalf of NHS Wales) and the National Institute for Health Research Birmingham Biomedical Research Centre, has been awarded £7.3M of UK Government funding to ensure more patients benefit from a new generation of breakthrough therapies.

£1.5M will come directly to NHS Wales and £550K to Trakcel, a Welsh software company developing scheduling/tracking software for advanced therapies which is based upon technology developed at Swansea University.

The funding will support the Welsh Government’s commitment to developing an Advanced Therapies Strategy which will enable these therapies to be brought to Welsh patients and Advanced Therapy Medicinal Product (ATMP) companies to reach the clinical market, whilst building expertise, capability and capacity across NHS Wales to benefit patient outcomes.

Speaking of the award, Frank Atherton, Chief Medical Officer for Wales, said: “We welcome the announcement of the successful partnership between Birmingham, Nottingham and Wales NHS centres in bidding for Innovate UK monies. The project is aligned with our ambition to support the development, availability and adoption of new innovative therapies for patients in Wales. Cell and gene-based advanced therapies offer exciting opportunities, not only for the way we treat people with previously incurable conditions, but also how we work together with industry and NHS Wales in bringing these treatments from bench to bedside.”

The NHS Wales role in the MW-ATTC consortium was led by the Welsh Blood Service, with support from Abertawe Bro Morgannwg and Cardiff & Vale University Health Boards along with the Life Sciences Hub Wales Special Interest Group on Cell and Gene Therapy, which brings together expertise from the Welsh NHS, Universities and industry in the Life Science sector.

As part of the contract award, one of the first advanced therapy treatment sites in Wales will be established within Abertawe Bro Morgannwg at the Joint Clinical Research Facility (JCRF) at Swansea University’s Medical School. The focus of the centre will be to develop the infrastructure, processes and skilled workforce required to enable patients to be cared for, from diagnosis through to post-treatment follow up.

Cath O’Brien, Director of the Welsh Blood Service and MW-ATTC Co-Director, said: “A significant opportunity exists to position Wales as a leader in clinical trial and routine delivery of cell and gene therapies to maximise Welsh patient benefit and opportunities for the national economy. The Welsh Government is committed to exploring these revolutionary developments in healthcare and we are excited to have worked alongside our consortium partners to secure funding through what was a highly competitive tendering process.”

One of the first products that will pass through the Welsh centres is that being developed by one of the consortium partners, Rexgenero and is intended to prevent the need for diabetes-related lower limb amputations for some no option patients. The incidence of diabetes is continuing to increase in Wales and already accounts for ~10% of the NHS Wales budget (£500M) with 200, 000 sufferers today rising to an estimated 500,000 by 2025. Currently around 2000 patients in Wales have non-healing lower limb ulcers that result in approximately 330 amputations per year.

The Midlands & Wales Advanced Therapy Treatment Centre (MW-ATTC) will identify barriers, challenges and solutions to facilitate future deployment and adoption of these transformative therapies within the UK healthcare system.

Advanced treatments, such as cell and gene therapies, show great promise for patients with chronic and terminal conditions that currently cannot be cured. Unlike conventional medicines, these new approaches often aim to selectively remove, repair, replace, regenerate and re-engineer a patient’s own genes, cells and tissues to restore normal function. The project will include potential treatments for arthritis, liver disease, several types of cancer, and diabetic ulcers.

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Education

Carmarthenshire students celebrate A Level and A.S. results

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CARMARTHENSHIRE County Council wishes to congratulate all of the county’s students that are receiving their A-Level and A.S. results today, Thursday 18th August 2022.

Whilst this year has seen a return to exam-based results, following two years of assessment-based grading during the COVID-19 pandemic, students and teachers have still had to contend with the ongoing impact of the last 2 years.

A total of 98.6% of A Level students in Carmarthenshire achieved A*-E, which is higher than the 97.3% in 2019 when exams were last sat.

Across Carmarthenshire, a total of 40.1% of A level students have received A or A* this year, which is vastly higher than the 24.9% when exams were last sat in 2019.

After 2 years without examinations, students at AS Level also had the opportunity this year to show what knowledge they had learned and skills they had developed, through a combination of exams and assessments, applicable to different courses. 91.8 % of AS students in Carmarthenshire achieved A-E grades which, again, is higher than in 2019.

Cllr. Glynog Davies, Cabinet Member for Education and Welsh Language said: “Congratulations to every single student receiving their A-Level and A.S. results today. These young people and their teachers have worked extremely hard, within the uncertain climate that exists due to the pandemic, and they should be very proud, as am I, of their fantastic achievements.

“I would like to take this opportunity to thank the students, teachers and support staff of Carmarthenshire as well as their families for their hard work over the last two years.”

In a joint statement, Carmarthenshire County Council’s Chief Executive, Wendy Walters and Director of Education and Children’s Services, Gareth Morgans added: “Congratulations to our A-Level and A.S. students for their, well deserved, excellent results. The last two years have been very challenging for students, teachers, support staff, families and friends and we are grateful to everyone for their commitment and support to each other during this period.

“These young people are a credit to their schools and our county, and we wish them every success for the future.”

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Education

St. Michaels School celebrates excellent A-Level results

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St. Michael’s pupils with their A-Level results

ST. MICHAEL’S School, Llanelli, is extremely pleased to announce another year of successful A-Level results, with 80.2% of all grades awarded either an A* or A grade.

The vast majority of pupils have earned a place at their chosen university to study courses such as Medicine, Veterinary Medicine and Economics.

This is the first year that traditional exams have resumed since the Covid-19 pandemic began with the majority of lessons in the first part of the A-Level being delivered online rather than in a classroom environment. This makes the results even more of an achievement considering the circumstances.

Headmaster Mr Benson Ferrari said: “We offer our sincere congratulations to our outgoing Year 13 class on the publication of their A-Level results, demonstrating that our pupils have worked so hard despite the challenges of returning to a conventional assessment approach.

“They approached the situation with resilience and dedication, which has resulted in grades that are truly representative of their ability.  I am confident that they will all go onto achieve great things at university and in their working lives.  

“We wish them the best as they move to this new and exciting stage of their education.  The preparation which St. Michael’s has provided will be built upon, along with our values and principles providing a lasting framework to tackle the challenges ahead.”

In 2020, St. Michael’s School was awarded The Sunday Times Welsh Independent School of the Decade and this was in part due to the excellent exam results that the school receives each year. 

St. Michael’s was also ranked 13th in The Times 2019 Co Ed League Table for UK Independent Schools, which was the last time that the results were published. The school hopes that this year’s results will continue to secure their place in the 2022 league table which will be published later this year.

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Education

Funding for music education trebled to the tune of £13.5m

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EVERY child will have the opportunity to benefit from music education as part of the Welsh Government’s plans for a national music service, which will help ensure no child misses out due to a lack of means.

As the National Plan for Music Education is published, the Minister for Education has confirmed funding will be trebled, with £13.5m being invested over the next three years.

The plan will make access to music education fairer and more consistent across Wales, with a particular focus on learners from low-income households and those with Additional Learning Needs. Support will be available for children and young people to access and progress with music tuition, with learners from disadvantaged and under-represented groups supported to join music ensembles.

The plan includes a number of key work programmes such as:

A review on music tutors’ terms and conditions, to ensure they are treated equitably and are recognised properly.
A ‘First Experiences’ programme to offer children in primary schools a minimum of half a term of musical instrument taster sessions, delivered by trained and skilled music practitioners.
A ‘Making Music with Others’ initiative, including opportunities for children and young people in secondary schools to gain industry experience through working alongside musicians and creative industries
A new national instrument and equipment library to support access to a resource bank to be shared across Wales.
These programmes will be rolled out from September 2022, supporting schools and settings to give all children and young people from the ages of 3 to 16 the opportunity to learn to play an instrument as well as singing and making music in our schools and our communities.

The National Music Service will operate as a ‘hub’, with the Welsh Local Government Association co-ordinating the Music Service’s programmes with a wide range of organisations. It will help schools and settings in their delivery of the Curriculum for Wales and provide more diverse opportunities for children and young people to experience music outside schools and settings.

First Minister of Wales, Mark Drakeford and the Minister for Education and Welsh Language, Jeremy Miles, visited St Joseph’s Cathedral Primary School in Swansea to see a cluster of primary school children taking part in a ‘Play Along’ session led by Swansea Music Service.

First Minister Mark Drakeford said:

“The establishment of a National Music Service for Wales is an important commitment in our Programme for Government and I’m delighted that we are delivering on this pledge.

“Learning an instrument was a formative part of my upbringing and a lack of money should not be a barrier to any young person who wants to learn to play music. We are fortunate in Wales to have a strong tradition of school, county and national ensembles, and we want to make sure that our children and young people are able to play a full part in these. This funding will support music services in schools and within the community to help nurture our young musical talent.”

The Minister for Education and the Welsh Language, Jeremy Miles said:

“Our vision is for all children and young people across Wales, regardless of background, to have the chance to learn to play an instrument. The plan we are publishing today, backed by funding, will help deliver that vision.

“For too long, the chance to learn an instrument and develop musical skills has been for those few whose families and carers who can afford tuition. I want to make sure everyone has the opportunity to access music tuition, and that’s why we’re making this significant investment to deliver a range of activities for our children and young people to learn and experience the joy of music.

“The development of the National Music Service will ensure that we nurture our next generation and continue to produce new talent and showcase Wales to the world.”

WLGA Chief Executive Chris Llewelyn said:

“We are proud to work with the Welsh Government on delivering this vital service to children across Wales. Many families in Wales can’t afford an instrument, and this funding will go a long way to opening doors to children across Wales to have the opportunity of learning an instrument.

“Playing an instrument and reading music is a very important skill for a child, and music brings enormous joy to children. Local authorities believe that children across Wales will have better access to instruments, and this plan will develop many future talented musicians, and support pupils to develop their musical skills.”

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