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Education

Swansea Uni to deliver advanced therapies

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A significant opportunity: University a centre for cell and gene therapies

SWANSEA U​NIVERSITY’S​ Medical School, through its partnership with Abertawe Bro Morgannwg University Health Board, is to be one of the centres to deliver advanced medical therapies to Wales, which is part of a major investment announced by Welsh Blood Services.

A recently formed health consortium, jointly led by the Welsh Blood Service (on behalf of NHS Wales) and the National Institute for Health Research Birmingham Biomedical Research Centre, has been awarded £7.3M of UK Government funding to ensure more patients benefit from a new generation of breakthrough therapies.

£1.5M will come directly to NHS Wales and £550K to Trakcel, a Welsh software company developing scheduling/tracking software for advanced therapies which is based upon technology developed at Swansea University.

The funding will support the Welsh Government’s commitment to developing an Advanced Therapies Strategy which will enable these therapies to be brought to Welsh patients and Advanced Therapy Medicinal Product (ATMP) companies to reach the clinical market, whilst building expertise, capability and capacity across NHS Wales to benefit patient outcomes.

Speaking of the award, Frank Atherton, Chief Medical Officer for Wales, said: “We welcome the announcement of the successful partnership between Birmingham, Nottingham and Wales NHS centres in bidding for Innovate UK monies. The project is aligned with our ambition to support the development, availability and adoption of new innovative therapies for patients in Wales. Cell and gene-based advanced therapies offer exciting opportunities, not only for the way we treat people with previously incurable conditions, but also how we work together with industry and NHS Wales in bringing these treatments from bench to bedside.”

The NHS Wales role in the MW-ATTC consortium was led by the Welsh Blood Service, with support from Abertawe Bro Morgannwg and Cardiff & Vale University Health Boards along with the Life Sciences Hub Wales Special Interest Group on Cell and Gene Therapy, which brings together expertise from the Welsh NHS, Universities and industry in the Life Science sector.

As part of the contract award, one of the first advanced therapy treatment sites in Wales will be established within Abertawe Bro Morgannwg at the Joint Clinical Research Facility (JCRF) at Swansea University’s Medical School. The focus of the centre will be to develop the infrastructure, processes and skilled workforce required to enable patients to be cared for, from diagnosis through to post-treatment follow up.

Cath O’Brien, Director of the Welsh Blood Service and MW-ATTC Co-Director, said: “A significant opportunity exists to position Wales as a leader in clinical trial and routine delivery of cell and gene therapies to maximise Welsh patient benefit and opportunities for the national economy. The Welsh Government is committed to exploring these revolutionary developments in healthcare and we are excited to have worked alongside our consortium partners to secure funding through what was a highly competitive tendering process.”

One of the first products that will pass through the Welsh centres is that being developed by one of the consortium partners, Rexgenero and is intended to prevent the need for diabetes-related lower limb amputations for some no option patients. The incidence of diabetes is continuing to increase in Wales and already accounts for ~10% of the NHS Wales budget (£500M) with 200, 000 sufferers today rising to an estimated 500,000 by 2025. Currently around 2000 patients in Wales have non-healing lower limb ulcers that result in approximately 330 amputations per year.

The Midlands & Wales Advanced Therapy Treatment Centre (MW-ATTC) will identify barriers, challenges and solutions to facilitate future deployment and adoption of these transformative therapies within the UK healthcare system.

Advanced treatments, such as cell and gene therapies, show great promise for patients with chronic and terminal conditions that currently cannot be cured. Unlike conventional medicines, these new approaches often aim to selectively remove, repair, replace, regenerate and re-engineer a patient’s own genes, cells and tissues to restore normal function. The project will include potential treatments for arthritis, liver disease, several types of cancer, and diabetic ulcers.

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Community

Strictly Cymru brings dancing a-plenty to 2020

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Disabled people from all over Wales have waltzed into 2020 for Strictly Cymru – the country’s renowned inclusive dance competition.

Run by charity Leonard Cheshire, in partnership with the national governing body Paradance UK, the competition has seen dancers in both inclusive and wheelchair-specific categories compete in six heats across South Wales, in preparation for the grand final on 6 June. Strictly Cymru is now in its third year.

Winning in the inclusive categories at the Carmarthen heat on 17 January were Coleg Sir Gar students Kieron, Toby, Thomas, and Max, as well as Richard, who came independently from Coleshill Day Centre in Llanelli and wowed the judges with his Michael Jackson inspired fast feet and moonwalk. A few days later, Rebecca, Chloe, and Anesha from Heronsbridge School lifted the trophy at the Bridgend heat on 21 January.

Gower College students Daniel and Carys wowed the judges with their synchronised dancing at the Cardiff heat, while Coleg Gwent student Matthew secured a place on the final in the inclusive heat held in Newport last week.

Meanwhile, in the wheelchair dance category, dancers Chad and Ben took gold in Carmarthen and Bridgend respectively. The Carmarthen heat rang with the sound of Chad’s catchphrase of “Absolutely fantastic!”

Then, the fifth heat in Cardiff saw the youngest person to take part in Strictly to date, five-year-old Inga, win in the wheelchair category, before Robin John won the final wheelchair heat in Newport after being inspired by his partner Dianne, who was highly commended in last year’s competition grand final.

Dance instructors from Paradance UK also took the participants, who came from schools the community and Leonard Cheshire services in the area, through their paces ahead of each dance-off to give everyone the best chance at reaching the final.

Chad said: “It has been a really great two days and I’ve enjoyed getting to know new people and learn tango. I’m looking forward to the final.”

Robin John, winning at Newport, said: “It’s absolutely wonderful, I’ve tried before and lost, but it feels on a whole different planet to win a heat! I’m looking forward to the final and don’t mind which genre of dance I get, I can adapt to most things.”

Ruth Jones, MP for Newport West, was a judge at the heat there. Ruth said: “I wasn’t sure what to expect beforehand, but it was amazing. As you walked into the room the enthusiasm hit you like a wave. It was so hard to choose a winner because they were all brilliant in their own way, everybody did the maximum they could possibly do.”

Alan Dear, Head of Theatre and Arts at Newport Live, helped support the Newport heat and said: “It is the most joyful thing I have done in years.”

The heats were open to people of all ages and abilities and the overall winners of the competition will be crowned in the Ffwrnes theatre in Llanelli on 6 June 2020.  There they will receive the coveted Strictly glitter ball trophy.

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Education

Lee Waters in School Council Summit

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LOCAL Member of the Senedd, Lee Waters has held the third Llanelli School Council Summit in the Welsh Parliament for secondary school pupils from across the constituency.

Over 70 pupils from schools right across the area visited the Senedd to learn how the Welsh Parliament works and take part in debates in the old Assembly debating chamber.

Pupils chose to debate lowering the voting age and banning diesel cars. They also had the opportunity to question the Minister for Health and Social Services, Vaughan Gething about their concerns and on his experiences as a Minister in the Welsh Government.

Lee Waters MS said

“Every year since becoming elected I’ve invited the school councils from the secondary schools across Llanelli to the Senedd for a School Council Summit. I’m really pleased that the event has grown and grown.”

“The pupils enthusiasm and grasp of the issues was really impressive, and it was great to hear their thoughts on some really important issues.”

“I was delighted to give pupils a chance to discuss their ideas with the Health Minister Vaughan Gething, debate issues that are important to them, and get practical careers advice learn from past pupils at their schools who now work in Welsh public life.”

“I want to show that pupils from Llanelli can succeed at whatever they choose in life, and get them involved in Welsh democracy.”

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Community

Llanelli MP & AM call for school transport solutions

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Llanelli’s MP and AM joined Tumble residents on Friday (15.01.20) to walk along the unlit path that children have been forced to take since a bus service to Maes y Gwendraeth school was scrapped.

A number of school bus routes in Carmarthenshire have been cancelled in response to UK Government legislation which has restricted the types of vehicles that bus companies can use. This has left many children who relied on these services with no safe way to get to school.

Nia Griffith MP and Lee Waters AM are working with local residents and councillors, like Dot Jones in Tumble, to find solutions that can be implemented by the County Council or UK Government.

Lee Waters AM said, “After carrying the bags and instruments of a Tumble pupil three miles to school on Friday morning it’s clear we need to get these services running again. I’ve been working with the Council and Welsh Government to try and find a common sense resolution to the problem of cancelled school buses right across Llanelli.

“It’s a complicated situation, and unfortunately the Welsh Government’s powers are limited, but we may have found a way forward if the UK Government are willing to be flexible. The Welsh Government has written to ask them to exempt school transport in Carmarthenshire from the new regulations which would allow the local services to resume.”

In addition to commercial school bus routes, there is also a scheme for pupils to access spare places on the coaches that pick up children who live further away from school for a small fare. However, local parents have raised concerns about the availability of this scheme and the process by which places are allocated.

Nia Griffith MP said, “We must work together to find ways to restore bus transport as soon as possible, even if the situation is complex.

“I understand the County Council will now review the scheme which lets pupils use spare places on existing school buses, but this needs to be done as quickly and effectively as possible to ensure the maximum number of pupils benefit.

“It is crazy to have buses with spare capacity passing the bus stop and leaving pupils to walk. But we need transport back for all pupils who have lost it.”

Cllr Rob James, who joined the walk to Ysgol Maes y Gwendraeth on Friday, said: “The bus services that have been withdrawn are vital services to many of our communities and must be retained.

“The local ward Councillors and I are thrilled with the support we are getting from the local MP and AM to solve these issues and we hope that there can be a resolution shortly.”

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